Associate Professor Jun Lu

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Associate Professor

Email: jun.lu@aut.ac.nz

ORCID: ORCID logo https://orcid.org/0000-0003-0225-6643

Links to relevant web pages:

Academic appointments:

  • Associate Professor, Auckland University of Technology (2009 - ongoing)
  • Head of Research, Auckland University of Technology (2009 - ongoing)
  • Research Fellow, University of Auckland (2004 - 2009)

Qualifications:

  • PhD, University of Auckland
  • MSc (Hon), University of Auckland
  • BSc, East China Normal University

Overview:

Dr. Jun Lu gained PhD and MSc degrees from University of Auckland and BSc degree from East China Normal University. He joined AUT since 2009 and established the Biomedical Science major. He specialises in pharmacology, natural bioactive compounds/products, nutrition, metabolic diseases, cancer, and food science. He is currently situated in School of Science and School of Interprofessional Health Studies. He is also a management team member of the Institute of Biomedical Technology.
Dr. Jun Lu is an Associate Investigator of two Centre of Research Excellence (CoRE) - Maurice Wilkins Centre for Molecular Diversity and Medical Technology Centre.
Internationally, Dr. Jun Lu the “Natural Compounds in Biomedicine” Section Editor-in-Chief of the journal Biomedicines, an Associate Editor of journals Frontiers in Pharmacology (impact factor 3.845), Biomolecules (impact factor 4.694), and Frontiers in Nutrition. He is a past Editorial Board member of Molecular Cancer Therapeutics (2008-2012), a past guest editor of Marine Drugs (impact factor 3.772) and a past Publication Committee member of the International Society for Magnetic Resonance in Medicine. He is also an active reviewer for more than 40 international journals.

Research interests:

The aims of my research are 1) to understand the molecular basis of obesity, type 2 diabetes, and heart and kidney complications associated with obesity and diabetes; 2) to identify novel targets to treat those diseases; 3) to find pharmacological treatment based on new targets; 4) to search for compounds from natural products for the treatment of cancer, obesity, diabetes and cardiovascular complications (including renal system) associated with obesity and diabetes; 5) to synthesise novel compounds based on rational design for the treatment of cancer and cardiac complication of obesity and diabetes; 6) to discover and develop neutraceutical products from New Zealand marine products with health benefits; and 7) to develop smart devices for health benefits.
I also have three research hobbies which are: 1) Use modern biomedical technology to study marine animals (i.e. using MRI technology to study fish hearing structure); 2) Use bioinformatic tools to study micro-organism in various environmental samples; and 3) Maori and Chinese interactions in New Zealand.
My expertise lies in the following areas. 1) Metabolic disease risk, treatment and prevention; 2) Nutraceutical, discovery and develop natural compounds in non-communicable disease treatment and prevention; 3) Pre-clinical and clinical pharmacology, especially drug metabolism and pre-clinical drug testing using animal models and cultured cell lines; 4) Analytical chemistry, characterisation and quantification of molecules of interest; 5) Medical imaging using MRI; 6) Polyamine metabolism and energy metabolism; and 7) Cardiovascular and renal function determination and biomarker identification.
My technical expertise including imaging using natural compounds extraction and identification, High-Field MRI and clinical MRI, chemical analysis using HPLC, LC-MS and GC-MS, animal experimentation, in vitro tissue experimentation, molecular biology technology and cell line experimentation.

Teaching summary:

PhD supervision
MSc supervision
MPhil supervision
Postgraduate course: Biomedical Science and Technology
Undergraduate course: Biomedical Science

Fields of research:

  • Analytical Chemistry
  • Macromolecular and Materials Chemistry
  • Medicinal and Biomolecular Chemistry
  • Biologically Active Molecules
  • Molecular Medicine
  • Organic Chemical Synthesis
  • Other Environmental Sciences
  • Biochemistry and Cell Biology
  • Enzymes
  • Food Sciences
  • Metabolic Medicine
  • Nephrology and Urology
  • Radiology and Organ Imaging
  • Chemotherapy
  • Molecular Targets
  • Pharmacology and Pharmaceutical Sciences

Research outputs:

Journal articles

  • Odeleye, T., White, W. L., & Lu, J. (2019). Cytotoxicity of Extracts from New Zealand Surf Clams Against Organ Cancer Cell Lines.. Biomedicines, 7(2), 1-14. doi:10.3390/biomedicines7020025

  • Luo, Q., Hamid, N., Oey, I., Leong, S. Y., Kantono, K., Alfaro, A., & Lu, J. (2019). Physicochemical changes in New Zealand abalone (Haliotis iris) with varying pulsed electric field (PEF) processing and heat treatments. LWT - Food Science and Technology, 115, 108438. doi:10.1016/j.lwt.2019.108438

  • Kong, Q., Ren, X., Qi, J., Yu, J., Lu, J., & Wang, S. (2019). Carbon-carbon double bond and resorcinol in resveratrol and its analogues: What is the characteristic structure in quenching singlet oxygen?. Biomolecules, 9(7). doi:10.3390/biom9070268

  • Chen, Y., Lu, J., Nemati, R., Plank, L. D., & Murphy, R. (2019). Acute changes of bile acids and FGF19 after sleeve gastrectomy and Roux-en-Y gastric bypass. Obesity Surgery. doi:10.1007/s11695-019-04040-x

  • Glossop, H. D., De Zoysa, G. H., Hemar, Y., Cardoso, P., Wang, K., Lu, J., . . . Sarojini, V. (2019). Battacin-inspired ultrashort peptides: Nanostructure analysis and antimicrobial activity. Biomacromolecules, 20(7), 2515-2529. doi:10.1021/acs.biomac.9b00291

  • Dulson, D. K., Gibson, C. A., Kilding, A. E., Lu, J., & Pook, C. (2019). Does caffeine exert dose-response effects on saliva secretory IgA following prolonged submaximal running?. Translational Sports Medicine, 2(4), 178-185. doi:10.1002/tsm2.73

  • Odeleye, T., White, W. L., & Lu, J. (2019). Extraction techniques and potential health benefits of bioactive compounds from marine molluscs: a review.. Food and Function, 10, 2278-2289. doi:10.1039/c9fo00172g

  • Singh, R. G., Cervantes, A., Kim, J. U., Nguyen, N. N., DeSouza, S. V., Dokpuang, D., . . . Petrov, M. S. (2019). Intrapancreatic fat deposition and visceral fat volume are associated with the presence of diabetes after acute pancreatitis. American Journal of Physiology: Gastrointestinal and Liver Physiology, 316(6), G806-G815. doi:10.1152/ajpgi.00385.2018

  • Kong, Q., Zhang, L., An, P., Qi, J., Yu, X., Lu, J., & Ren, X. (2019). Antifungal mechanisms of α-terpineol and terpene-4-alcohol as the critical components of Melaleuca alternifolia oil in the inhibition of rot disease caused by Aspergillus ochraceus in postharvest grapes. Journal of Applied Microbiology, 126(4), 1161-1174. doi:10.1111/jam.14193

  • Koh, H. S. A., Lu, J., & Zhou, W. (2019). Structure characterization and antioxidant activity of fucoidan isolated from Undaria pinnatifida grown in New Zealand. Carbohydrate Polymers, 212, 178-185. doi:10.1016/j.carbpol.2019.02.040

  • Myint, K., Biswas, R., Li, Y., Jong, N., Jamieson, S., Liu, J., . . . McKeage, M. (2019). Identification of MRP2 as a targetable factor limiting oxaliplatin accumulation and response in gastrointestinal cancer. Scientific Reports, 9(1), 1-12. doi:10.1038/s41598-019-38667-8

  • Zhao, Y., Zheng, Y., Wang, J., Ma, S., Yu, Y., White, W. L., . . . Lu, J. (2018). Fucoidan extracted from Undaria pinnatifida: Source for nutraceuticals/functional foods. Marine Drugs, 16(9). doi:10.3390/md16090321

  • Dantzic, D., Noel, P., Merien, F., Liu, D. X., Lu, J., Han, H., . . . Li, Y. (2018). The effects of synthetically modified natural compounds on ABC transporters. Pharmaceutics, 10(3). doi:10.3390/pharmaceutics10030127

  • Lu, L. W., Monro, J., Lu, J., & Rush, E. (2018). The effect of cold treatment of parboiled rice with lowered glycaemic potency on consumer liking and acceptability. Foods, 7(12), 1-12. doi:10.3390/foods7120207

  • Rowan, J. A., Rush, E. C., Plank, L. D., Lu, J., Obolonkin, V., Coat, S., & Hague, W. M. (2018). Metformin in gestational diabetes: The offspring follow-up (MiG TOFU): Body composition and metabolic outcomes at 7-9 years of age. Obstetrical and Gynecological Survey, 73(10), 565-567. doi:10.1097/01.ogx.0000547170.99000.49

  • Yang, X., Wang, S., Trangle, S. S., Li, Y., White, W. L., Li, J., . . . Lu, J. (2018). Investigation of different molecular weight Fucoidan fractions derived from New Zealand Undaria pinnatifida in combination with GroA therapy in prostate cancer cell lines. Marine Drugs, 16(11). doi:10.3390/md16110454

  • Hassouna, A., Lu, J., Merien, F., White, W., & White, L. (2018). Fucoidan extracted from New Zealand Undaria pinnatifida – physicochemical comparison against five other fucoidans: Unique low molecular weight fraction bioactivity in breast cancer cell lines. Marine Drugs, 16(12), 1-25. doi:10.3390/md16120461

  • Bi, D., Yu, B., Han, Q., Lu, J., White, W. L., Lai, Q., . . . Xu, X. (2018). Immune activation of RAW264.7 macrophages by low molecular weight fucoidan extracted from New Zealand Undaria pinnatifida. Journal of Agricultural and Food Chemistry, 66(41), 10721-10728. doi:10.1021/acs.jafc.8b03698

  • Nemati, R., Lu, J., Dokpuang, D., Booth, M., Plank, L. D., & Murphy, R. (2018). Increased Bile Acids and FGF19 After Sleeve Gastrectomy and Roux-en-Y Gastric Bypass Correlate with Improvement in Type 2 Diabetes in a Randomized Trial. Obesity Surgery, 28(9). doi:10.1007/s11695-018-3216-x

  • Aipire, A., Chen, Q., Cai, S., Li, J., Fu, C., Ying, T., . . . Li, J. (2018). N-butanol subfraction of Brassica Rapa L. promotes reactive oxygen species production and induces apoptosis of A549 lung adenocarcinoma cells via mitochondria-dependent pathway. Molecules, 23(7), 1-12. doi:10.3390/molecules23071687

  • Rowan, J. A., Rush, E. C., Plank, L. D., Lu, J., Obolonkin, V., Coat, S., & Hague, W. M. (2018). Metformin in gestational diabetes: The offspring follow-up (MiG TOFU): Body composition and metabolic outcomes at 7-9 years of age. BMJ Open Diabetes Research and Care, 6. doi:10.1136/bmjdrc-2017-000456

  • Bi, D., Lai, Q., Cai, N., Li, T., Zhang, Y., Han, Q., . . . Xu, X. (2018). Elucidation of the molecular-mechanisms and in vivo evaluation of the anti-inflammatory effect of alginate-derived seleno-polymannuronate. Journal of Agricultural and Food Chemistry, 66(9). doi:10.1021/acs.jafc.7b05719

  • You, X., Wu, D., Wei, H., Xie, B., & Lu, J. (2018). Fluoroquinolones and Β-lactam antibiotics and antibiotic resistance genes in autumn leachates of seven major municipal solid waste landfills in China. Environment International, 113. doi:10.1016/j.envint.2018.02.002

  • Wang, C., Li, Y., Lu, J., Deng, X., Li, H., & Hu, Z. (2018). Effect of overexpression of LPAAT and GPD1 on lipid synthesis and composition in green microalga Chlamydomonas reinhardtii. Journal of Applied Phycology, 30(3), 1711-1719. doi:10.1007/s10811-017-1349-2

  • Fielder, G. C., Yang, T. W. S., Razdan, M., Li, Y., Lu, J., Perry, J. K., . . . Liu, D. X. (2018). The GDNF family: A role in cancer?. Neoplasia, 20(1). doi:10.1016/j.neo.2017.10.010

  • Pearce, J., Sabetian, A., Keyser, L., Wang, S. K., & Lu, J. (2018). Assessing sperm membrane viability using flow cytometry in farmed New Zealand giant kokopu Galaxias argenteus. New Zealand Journal of Marine and Freshwater Research, 52(3), 362-371. doi:10.1080/00288330.2017.1394883

  • Sotelo, K. A. G., Hamid, N., Oey, I., Pook, C., Gutierrez-Maddox, N., Ma, Q., . . . Lu, J. (2018). Red cherries (Prunus avium var. Stella) processed by pulsed electric field – Physical, chemical and microbiological analyses. Food Chemistry, 240. doi:10.1016/j.foodchem.2017.08.017

  • Wang, J., Chan, C., Huang, F. -W., Xie, J. -F., Xu, H., Ho, K. -W., . . . He, Z. -D. (2017). Interaction mechanism of pepsin with a natural inhibitor gastrodin studied by spectroscopic methods and molecular docking. Medicinal Chemistry Research, 26(2). doi:10.1007/s00044-016-1760-2

  • Fu, Z., Yoo, M. J. Y., Zhou, W., Zhang, L., Chen, Y., & Lu, J. (2017). Effect of (−)-epigallocatechin gallate (EGCG) extracted from green tea in reducing the formation of acrylamide during the bread baking process. Food Chemistry, 242. doi:10.1016/j.foodchem.2017.09.050

  • Kong, C. H. Z., Hamid, N., Ma, Q., Lu, J., Wang, B. G., & Sarojini, V. (2017). Antifreeze peptide pretreatment minimizes freeze-thaw damage to cherries: an in-depth investigation. LWT - Food Science and Technology, 84. doi:10.1016/j.lwt.2017.06.002

  • Lu, L. W., Venn, B., Lu, J., Monro, J., & Rush, E. (2017). Effect of cold storage and reheating of parboiled rice on postprandial glycaemic response, satiety, palatability and chewed particle size distribution. Nutrients, 9(5). doi:10.3390/nu9050475

  • Fang, W., Bi, D., Zheng, R., Cai, N., Xu, H., Zhou, R., . . . Xu, X. (2017). Identification and activation of TLR4-mediated signalling pathways by alginate-derived guluronate oligosaccharide in RAW264.7 macrophages. Scientific Reports, 7. doi:10.1038/s41598-017-01868-0

  • Bugde, P., Biswas, R., Merien, F., Lu, J., Liu, D. X., Chen, M., . . . Li, Y. (2017). The therapeutic potential of targeting ABC transporters to combat multi-drug resistance. Expert Opinion on Therapeutic Targets, 21(5). doi:10.1080/14728222.2017.1310841

  • Singh, R. G., Yoon, H. D., Wu, L. M., Lu, J., Plank, L. D., & Petrov, M. S. (2017). Ectopic fat accumulation in the pancreas and its clinical relevance: A systematic review, meta-analysis, and meta-regression. Metabolism: Clinical and Experimental, 69. doi:10.1016/j.metabol.2016.12.012

  • Thakur, V., Lu, J., Roscilli, G., Aurisicchio, L., Cappelletti, M., Pavoni, E., . . . Bedogni, B. (2017). The natural compound fucoidan from New Zealand Undaria pinnatifida synergizes with the ERBB inhibitor lapatinib enhancing melanoma growth inhibition. Oncotarget, 8(11). doi:10.18632/oncotarget.14437

  • Wang, X., Xie, B., Zhang, C., Shen, Y., & Lu, J. (2017). Quantitative impact of influent characteristics on nitrogen removal via anammox and denitrification in a landfill bioreactor case. Bioresour Technology, 224. Retrieved from http://dx.doi.org/10.1016/j.biortech.2016.11.078

  • Zhao, Y., Li, Y., Jiang, K., Wang, J., White, W. L., Yang, S., & Lu, J. (2017). Rapid detection of Listeria monocytogenes in food by biofunctionalized magnetic nanoparticle based on nuclear magnetic resonance. Food Control, 71. doi:10.1016/j.foodcont.2016.06.028

  • Wu, Z., Shen, L., Han, Q., Lu, J., Tang, H., Xu, X., . . . Hu, Z. (2016). Mechanism and Nature of Inhibition of Trypsin by Ligupurpuroside A, a Ku-Ding Tea Extract, Studied by Spectroscopic and Docking Methods. Food Biophysics. doi:10.1007/s11483-016-9465-0

  • Long, J., Gholizadeh, H., Lu, J., Bunt, C., & Seyfoddin, A. (2016). Review: Application of Fused Deposition Modelling (FDM) method of 3D printing in drug delivery. Curr Pharm Des, 22(46). Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/27784251

  • LW, L., J, M., Lu, J., & Rush, E. (2016). Effect of Cold Storage, Reheating, and Particle Sizes on In Vitro Glucose Release and Starch Digestibility among Five Rice Products in Auckland, New Zealand. Journal of Rice Research, 4(3). doi:10.4172/2375-4338.1000171

  • Feng, Q., Han, L., Tan, X., Zhang, Y., Meng, T., Lu, J., & Lv, J. (2016). Bacterial and archaeal diversities in Maotai Section of the Chishui River, China. Current Microbiology, 73(6). doi:10.1007/s00284-016-1142-5

  • Nemati, R., Lu, J., Tura, A., Smith, G., & Murphy, R. (2016). Acute changes in non-esterified fatty acids in patients with type 2 diabetes receiving bariatric surgery. Obesity Surgery, 27(3). doi:10.1007/s11695-016-2323-9

  • Li, J., Chen, C., Lu, J., Lei, A., & Hu, Z. (2016). Temporal patterns in bacterioplankton community composition in three reservoirs of similar trophic status in Shenzhen, China. International Journal of Environmental Research and Public Health, 13(6). doi:10.3390/ijerph13060599

  • Nemati, R., Lu, J., Ramachandran, V., Etemad, A., Heidari, M., Yahya, M. J., . . . Ismail, P. (2016). Association between the C34T polymorphism of the AMPD1 gene and essential hypertension in Malaysian patients. Genetics and Molecular Research, 15(2). doi:10.4238/gmr.15026241

  • Feng, X., Dong, H., Yang, P., Yang, R., Lu, J., Lv, J., & Sheng, J. (2016). Culture-Dependent and -Independent Methods to Investigate the Predominant Microorganisms Associated with Wet Processed Coffee. Current Microbiology. doi:10.1007/s00284-016-1047-3

  • Zhang, W., Yang, R., Fang, W., Yan, L., Lu, J., Sheng, J., & Lv, J. (2016). Characterization of thermophilic fungal community associated with pile fermentation of Pu-erh tea. International Journal of Food Microbiology, 227. doi:10.1016/j.ijfoodmicro.2016.03.025

  • Odeleye, T., Li, Y., White, W. L., Nie, S., Chen, S., Wang, J., & Lu, J. (2016). The antioxidant potential of the New Zealand surf clams. Food Chemistry, 204. doi:10.1016/j.foodchem.2016.02.120

  • Thomas, F., Smith, G. C., Lu, J., Babor, R., Booth, M., Beban, G., . . . Murphy, R. (2016). Differential Acute Impacts of Sleeve Gastrectomy, Roux-en-Y Gastric Bypass Surgery and Matched Caloric Restriction Diet on Insulin Secretion, Insulin Effectiveness and Non-Esterified Fatty Acid Levels Among Patients with Type 2 Diabetes. Obesity Surgery. doi:10.1007/s11695-015-2038-3

  • Balbas, J., Hamid, N., Liu, T., Kantono, K., Robertson, J., White, W. L., . . . Lu, J. (2015). Comparison of physicochemical characteristics, sensory properties and volatile composition between commercial and New Zealand made wakame from Undaria pinnatifida. Food Chemistry, 186, 168-175. doi:10.1016/j.foodchem.2015.03.079

  • Zhou, A. Y., Robertson, J., Hamid, N., Ma, Q., & Lu, J. (2015). Changes in total nitrogen and amino acid composition of New Zealand Undaria pinnatifida with growth, location and plant parts. Food Chemistry, 186. doi:10.1016/j.foodchem.2014.06.016

  • Liu, L. S., & Lu, J. (2015). Contesting transnational mobility among New Zealand’s Chinese migrants from an economic perspective. Journal of Chinese Overseas, 11.

  • Ying, M., Huang, F., Ye, H., Xu, H., Shen, L., Huan, T., . . . Zhou, K. (2015). Study on interaction between curcumin and pepsin by spectroscopic and docking methods.. International Journal of Biological Macromolecules, 79. doi:10.1016/j.ijbiomac.2015.04.057

  • Balbas, J., Hamid, N., Liu, T., Kantono, K., Robertson, J., White, W. L., . . . Lu, J. (2015). Comparison of physicochemical characteristics, sensory properties and volatile composition between commercial and New Zealand made wakame from Undaria pinnatifida. Food Chemistry, 186. doi:10.1016/j.foodchem.2015.03.079

  • Jo-Avila, M., Al-Jumaily, A. M., & Lu, J. (2015). Relaxant effect of superimposed length oscillation on sensitized airway smooth muscle. Americal Journal of Physiology: Lung Cellular and Molecular Physiology, 308(5). doi:10.1152/ajplung.00218.2014

  • Tait, I. S., Li, Y., & Lu, J. (2015). Effects of PTEN on the longevity of cultured human umbilical vein endothelial cells: The role of antioxidants. International Journal of Molecular Medicine, 35(1). doi:10.3892/ijmm.2014.1999

  • Mak, W., Wang, S. K., Liu, T., Hamid, N., Li, Y., Lu, J., & White, W. L. (2014). Anti-proliferation potential and content of fucoidan extracted from sporophyll of New Zealand Undaria pinnatifida. Frontiers in Nutrition, 1. doi:10.3389/fnut.2014.00009

  • Brett-Morris, A., Wright, B. M., Seo, Y., Pasupuleti, V., Zhang, J., Lu, J., . . . Welford, S. M. (2014). The polyamine catabolic enzyme SAT1 modulates tumorigenesis and radiation response in GBM. Cancer Research. doi:10.1158/0008-5472.CAN-14-1249

  • Huang, Z., Xie, B., Yuan, Q., Xu, W., & Lu, J. (2014). Microbial community study in newly established Qingcaosha Reservoir of Shanghai, China. Applied Microbiology and Biotechnology. doi:10.1007/s00253-014-5928-8

  • Tian, J., Lu, J., Zhang, Y., Li, J. C., Sun, L. C., & Hu, Z. L. (2014). Microbial community structures and dynamics in the O3/BAC drinking water treatment process. International Journal for Environmental Research and Public Health, 11(6). doi:10.3390/ijerph110606281

  • Wang, S. K., Li, Y., White, W. L., & Lu, J. (2014). Extracts from New Zealand Undaria pinnatifida containing fucoxanthin as potential functional biomaterials against cancer in vitro. Journal of Functional Biomaterials, 5(2). doi:10.3390/jfb5020029

  • Boulom, S., Robertson, J., Hamid, N., Ma, Q., & Lu, J. (2014). Seasonal changes in lipid, fatty acid, α-tocopherol and phytosterol contents of seaweed, Undaria pinnatifida, in the Marlborough Sounds, New Zealand. Food Chemistry, 161. doi:10.1016/j.foodchem.2014.04.007

  • Huang, F., Zhang, Y., Zhu, Y., Wang, P., Lu, J., & Lv, J. (2014). Flavobacterium qiangtangensis sp. nov., Isolated from Qiangtang Basin in Qinghai-Tibetan Plateau, China. Current Microbiology, 69(3). doi:10.1007/s00284-014-0579-7

  • Luo, W., Chen, H., Lei, A., Lu, J., & Hu, Z. (2014). Estimating cyanobacteria community dynamics and its relationship with environmental factors. International Journal of Environmental Research and Public Health, 11(1). doi:10.3390/ijerph110101141

  • Tait, I., Li, Y., & Lu, J. (2013). PTEN, longevity and age-related diseases. Biomedicines, 1(1). doi:10.3390/biomedicines1010017

  • Caiger, P. E., Montgomery, J. C., Bruce, M., Lu, J., & Radford, C. A. (2013). A proposed mechanism for the observed ontogenetic improvement in the hearing ability of hapuka (Polyprion oxygeneios). Journal of Comparative Physiology A: Neuroethology, Sensory, Neural, and Behavioral Physiology, 199(7).

  • Radford, C. A., Montgomery, J. C., Caiger, P., Johnston, P., Lu, J., & Higgs, D. M. (2013). A novel hearing specialization in the New Zealand bigeye, Pempheris adspersa. Biology Letters, 9(4). doi:10.1098/rsbl.2013.0163

  • Mak, W., Hamid, N., Liu, T., Lu, J., & White, W. L. (2013). Fucoidan from New Zealand Undaria pinnatifida: Monthly variations and determination of antioxidant activities. Carbohydrate Polymers, 95(1).

  • Lu, J., Pontré, B., Pickup, S., Choong, S. Y., Li, M., Xu, H., . . . Cooper, G. J. (2013). Treatment with a copper-selective chelator causes substantive improvement in cardiac function of diabetic rats with left-ventricular impairment. Cardiovascular Diabetology, 12. doi:10.1186/1475-2840-12-28

  • Li, X., Lu, J., Ren, H., Chen, T., Gao, L., Di, L., . . . et al. (2013). Combining multiple serum biomarkers in tumor diagnosis: A clinical assessment. Molecular and Clinical Oncology, 1(1). doi:10.3892/mco.2012.23

  • Fung, A., Hamid, N., & Lu, J. (2013). Fucoxanthin content and antioxidant properties of Undaria pinnatifida. Food Chemistry, 136.

  • Xie, B., Xiong, S., Liang, S., Hu, C., Zhang, X., & Lu, J. (2012). Performance and bacterial compositions of aged refuse reactors treating mature landfill leachate. Bioresource Technology, 103(1). Retrieved from http://www.sciencedirect.com.ezproxy.aut.ac.nz/

  • Zhu, Q., Wu, X., Xiao, J., Cheng, X., Lu, J., Liu, Z., & Xu, H. (2012). Prediction of the structure and antigenic epitopes of cashew allgergn Ana o 2. Journal of Food Science and Biotechnology (China), 31.

  • Liu, J. J., Lu, J., & McKeage, M. J. (2012). Membrane transporters as determinants of the pharmacology of platinum anticancer drugs. Current Cancer Drug Targets, 12(8). Retrieved from http://www.benthamscience.com/contents-JCode-CCDT-Vol-00000012-Iss-00000008.htm

  • Li, Y., Lu, J., & Paxton, J. (2012). The role of ABC and SLC transporters in the pharmacokinetics of dietary and herbal phytochemicals and their interactions with xenobiotics. Current Drug Metabolism, 13(5). Retrieved from http://www.ingentaconnect.com/content/ben/cdm/2012/00000013/00000005/art00010

  • Chen, H., Fu, L., Luo, L., Lu, J., White, W. L., & Hu, Z. (2012). Induction and resuscitation of the viable but nonculturable state in a cyanobacteria-lysing bacterium isolated from cyanobacterial bloom. Microbial Ecology, 63(1). doi:10.1007/s00248-011-9928-2

  • White, D. E., Al-Jumaily, A. M., Bartley, J., & Lu, J. (2011). Correlation of nasal morphology to air-conditioning and clearance function. Respiratory Physiology and Neurobiology, 179(2-3). doi:10.1016/j.resp.2011.07.009

  • Xiao, J., Wu, X., Wang, L., Lu, J., & Xu, H. (2011). Bioinformatics of profilin protein from peanut. Immunological journal (China), 27.

  • Xu, H., Zhu, Q. Q., Lu, J., Chen, X. J., Luo, H. M., Xiao, J., . . . Liang, Y. (2010). Studies on Thermodynamic Nature of Steroselectivity for Ruthenium(II).Polypyridyl Complex Binding to DNA. Inorganic Chemistry Communications, 13.

  • Xie, B., Lv, B. Y., Hu, C., Liang, S. B., Tang, Y., & Lu, J. (2010). Landfill leachate pollutant removal performance of a novel biofilter packed with mixture medium. Bioresource Technology, 101.

  • Xie, B., Gu, J. D., & Lu, J. (2010). The surface properties of bacteria from activated sludge in relation to bioflocculation. Journal of Environmental Sciences, 22(12).

  • Luo, H. M., Xiao, J., Wu, Y. L., Liu, Z. G., Lu, J., & Xu, H. (2010). Spectroscopic Studies on Refolding Process in vitro of Pan-allergen Profilin in Coco Pollen. Spectroscopy and Spectral Analysis, 30.

  • Luo, H. M., Xiao, J., Chen, J. C., Xu, H., Lu, J., Liu, Z. G., . . . Ji, L. N. (2010). Effect of Electronic Structures of Enantiomers of Ruthenium(II).Polypyridyl Complexes on DNA Binding Behaviors. Chinese Journal of Chemistry, 28.

  • Lu, J., Poppitt, S., Othman, A. A., Sunderland, T., Ruggeiro, K., Willett, M. S., . . . Cooper, G. J. S. (2010). Pharmacokinetics, Pharmacodynamics and Metabolism of Triethylenetetramine in Healthy Human Participants: An Open Label Trial. Journal of Clinical Pharmacology, 50.

  • Lu, J., Gong, D., Choong, S. Y., Xu, H., Chan, Y. K., Chen, X., . . . Cooper, G. J. S. (2010). Copper(II)-selective chelation restores function and antioxidant defences in cardiovascular tissues of diabetic rats: comparisons between triethylenetetramine and three less-selective transition-metal-targeted treatments. Diabetologia, 53.

  • Lu, J. (2010). Triethylenetetramine Pharmacology and Its Clinical Applications. Molecular Cancer Therapeutics, 9.

  • Jullig, M., Chen, X., Vazhoor, G., Middleditch, M. J., Hickey, A. J., Gong, D., . . . Cooper, G. J. S. (2010). Elluminating the molecular basis of diabetic arteriopathy: A proteomic comparison of the aortic tissue from diabetic and healthy rats. Proteomics, 10.

  • Gong, D., Chen, X., Middleditch, M., Huang, L., Amarsingh, G. V., Reddy, S., . . . Cooper, G. J. S. (2009). Quantitative proteomic profiling identifies new renal targets of copper(II)-selective chelation in the reversal of diabetic nephropathy in rats. Proteomics, 9(18). Retrieved from http://onlinelibrary.wiley.com.ezproxy.aut.ac.nz/doi/10.1002/pmic.200900285/pdf

  • Liu, L., & Lu, J. (2008). Looking at the other: Chinese and Maori youth perspectives. Asian and Pacific Migration Journal, 17(2). Retrieved from http://web.ebscohost.com.ezproxy.aut.ac.nz/

  • Gong, D., Lu, J., Chen, X., Reddy, S., Crossman, D., Glyn Jones, S., . . . Cooper, G. J. S. (2008). A copper(II)-selective chelator ameliorates diabetes-evoked renal fibrosis and albuminuria, and suppresses pathogenic TGF-ß activation in the kidneys of rats used as a model of diabetes. Diabetologia, 51(9). Retrieved from http://www.springerlink.com.ezproxy.aut.ac.nz/

  • Othman, A., Lu, J., Sunderland, T., & Cooper, G. J. S. (2007). Development and validation of a rapid HPLC method for the simultaneous determination of triethylenetetramine and its two main metabolites in human serum. Journal of Chromatography B, 860(1). Retrieved from http://www.sciencedirect.com.ezproxy.aut.ac.nz/

  • Lu, J., Chan, Y. -K., Poppitt, S. D., & Cooper, G. J. S. (2007). Determination of triethylene-tetramine (TETA) and its metabolites in human plasma and urine by liquid chromatography-mass spectrometry. Journal of Chromatography B, 859(1). Retrieved from http://www.sciencedirect.com.ezproxy.aut.ac.nz/

  • Lu, J., Chan, Y. -K., Gamble, G. D., Poppitt, S. D., Othman, A., & Cooper, G. J. S. (2007). Triethylene-tetramine and metabolites: Levels in relation to copper and zinc excretion in urine of healthy volunteers and type-2 diabetic patients. Drug Metabolism and Disposition, 35(2). Retrieved from http://dmd.aspetjournals.org/content/35/2/221.full.pdf+html

  • Gong, D., Lu, J., Chen, X., Choong, S. Y., Zhang, S., Chan, Y. K., . . . Cooper, G. J. S. (2006). Molecular changes evoked by Triethylenetetramine treatment in the extracelluar matrix of the heart and aorta in diabetic rats. Molecular Pharmacology, 70(6). Retrieved from http://molpharm.aspetjournals.org/

  • Lu, J., Helsby, N., Palmer, B. D., Tingle, M., Baguley, B. C., Kestell, P., & Ching, L. M. (2004). Metabolism of thalidomide in liver microsomes of mice, rabbits, and humans. Journal of Pharmacology and Experimental Therapeutics, 310(2). Retrieved from http://jpet.aspetjournals.org.ezproxy.aut.ac.nz/

  • Chung, F., Lu, J., Palmer, B. D., Kestell, P., Browett, P., Baguley, B. C., . . . Ching, L. M. (2004). Thalidomide pharmacokinetics and metabolite formation in mice, rabbits and multiple myeloma patients. Clinical Cancer Research, 10. Retrieved from http://clincancerres.aacrjournals.org.ezproxy.aut.ac.nz/

  • Lu, J., Palmer, B. D., Kestell, P., Browett, P., Baguley, B. C., Muller, G., & Ching, L. M. (2003). Thalidomide metabolites in mice and patients with multiple myeloma. Clinical Cancer Research, 9. Retrieved from http://clincancerres.aacrjournals.org.ezproxy.aut.ac.nz/

  • Wells, R. M. G., Lu, J., Hickey, A. J. R., & Jeffs, A. G. (2001). Ontogenetic changes in enzyme activities associated with energy production in the spiny lobster, Jasus edwardsii. Comparative Biochemistry and Physiology, Part B, 130(3). Retrieved from http://www.sciencedirect.com/

Book chapters

  • Al-Rawi, M. A., Al-Jumaily, A. M., Lowe, A., & Lu, J. (2012). Computational Fluid Dynamics in Arterial Fluid-Wall Interaction Modelling. In R. A. Arfi (Ed.), Systolic Blood Pressure: Influences, Associations and Management (pp. 135-154). New York: Nova Science Publishers.

  • Lu, J. (2009). Ancient Maori-Chinese ancestral links - A survey of the current western understandings. In M. Ip (Ed.), The Dragon and the Taniwha: Maori and Chinese in New Zealand (pp. 12-31). Auckland: Auckland University Press.

Conference contributions

  • Biswas, R., Merien, F., Lu, J., McKeage, M., & Li, Y. (2017). Silencing ABCC2 transporter gene enhances the oxaliplatin chemo-sensitivity in colorectal cancer cells. In Book of poster abstracts of the 2017 joint APSA-ASCEPT annual conference, Brisbane Australia. Brisbane, Queensland. Retrieved from https://www.asceptasm.com/2017-annual-scientific-meeting/program-workshops/

  • Biswas, R., Merien, F., Lu, J., Paxton, J., McKeage, M., & Li, Y. (2016). Modulation of multidrug resistance protein 2 (MRP2) by RNA interference (RNAi) increases the chemo-sensitivity of HepG2 cells to oxaliplatin. In Abstract and programme booklet (pp. 28). Nelson. Retrieved from http://www.queenstownresearchweek.org/

  • Plank, L., Lu, J., Rush, E., & Rowan, J. (2015). Visceral fat measured by DXA correlates with measurement by MRI in children.. In Proceedings of the ESPEN 2015 Congress. Portugal.

  • Lu, J., White, W. L., Li, Y., Wang, K. S., Al-Jumaily, A. M., Fung, A., . . . Hamid, N. (2015). Anticancer potential and antioxidant property of extracts from New Zealand seaweed Undaria pinnatifida – potential use in cancer treatment and cardiovascular improvement.. In Proceedings of the International Symposium on Phytochemicals in Medicine and Food (ISPMF 2015). Shanghai.

  • Jo-Avila, M. J., Roos, K., Al-Jumaily, A. M., & Lu, J. (2014). Super imposed length oscillations (SILO) and their effect on asthmatic models (acute and chronic) during an asthma attack. In ASME 2014 International Mechanical Engineering Congress & Exposition. Montreal.

  • Jo-Avila, M. J., Al-Jumaily, A. M., & Lu, J. (2014). Super imposed pressure oscillations (SIPO) and their effect on acute asthmatic models during an induced asthmatic attack. In Medical Science Congress of New Zealand. Queenstown.

  • Li, Y., Lu, W., Lu, J., Chen, M., & White, L. (2014). Effects of fucoxanthin on gemcitabine sensitivity in human lung cancer cells. In New Zealand Medical Science Congress 2014. Queenstown.

  • Lu, J., Rush, E., Plank, L., & Rowan, J. (2014). Magnetic resonance in MiGTOFU trial. In Proceedings of the Joint Meeting of International Society for Magnetic Resonance in Medicine-ESMRMB. Milan. Retrieved from http://www.ismrm.org/14/Accepted_Abstracts.pdf

  • Murphy, R., Lu, J., Zhao, L., & Orr, D. (2014). Impact of weight loss on fatty liver and type 2 diabetes among women of different ethnicities: A pilot study. In Annual Meeting of New Zealand Society for the Study of Diabetes. Queenstown.

  • Brett-Morris, A., Wright, B., Seo, Y., Spina, R., Bar, E., Zhang, J., . . . Welford, S. M. (2014). SAT1 (Spermidine/spermine-N1-acetyltrasferase 1) promotes radiation resistance in glioblastoma multiforme. In 105th Annual Meeting of the American Association for Cancer Research. San Diego, CA. Retrieved from http://www.abstractsonline.com/

  • Wang, S., Lu, J., Li, Y., & White, W. L. (2013). Anticancer potentials of fucoxanthin contents extracted from New Zealand Undaria pinnatifida. In Aquatic Science at the Interface Conference 2013. Hamilton.

  • White, W. L., Hamid, N., Lu, J., & Robertson, J. (2013). Utilisation of Undaria pinnatifida from Southern New Zealand. In 21st International Seaweed Symposium. Bali.

  • Jo-Avila, M., Al-Jumaily, A., Lu, J., & Sobrevia, L. (2013). Study of the combined effect of Isoproterenol and Mechanical Oscillations on the contractile response of airways from healthy and asthmatic subjects (in vivo). In ASME 2013 International Mechanical Engineering Congress & Exposition. San Diego, CA.

  • White, W. L., Alfaro, A. C., Lu, J., Hamid, N., Li, Y., Millar, R., . . . Yoo, M. (2013). Bioactive compounds and commercialisation of NZ marine products: Undaria pinnatifida and NZ Surf Clams. In NZIFST Conference 2013: Time for action. Hastings.

  • Li, Y., Lu, J., White, L., Wang, K., Lu, W., White, W. L., . . . Paxton, J. (2013). Phytochemicals and drug resistance in pancreatic cancer chemotherapy. In BIT’s 6th Annual World Cancer Congress. Xi’an.

  • Al-Rawi, M. A., Jo-Avila, M. J., Al-Jumaily, A., & Lu, J. (2012). A FLUID-STRUCTURE INTERACTION MODEL OF ATHEROSCLEROSIS AT THE ABDOMINAL AORTA. In IMECE2012-85912. Houston.

  • Jo-Avila, M. J., Al-Jumaily, A., Sobrevia, L., & Lu, J. (2012). Combined Effect of isoproterenol and mechanical oscillation on the contractile response of mice airway smooth muscle from healthy and asthmatic subjects. In 2012 ASME International Mechanical Engineering Congress and Exposition, November 9 – November 15, 2012 Houston, Texas. Houston.

  • Quitain, A. T.., Kai, T., Sasaki, M., Goto, M., Wang, K., Lu, J., . . . White, W. L. (2012). Supercritical carbon dioxide extraction of fucoxanthin-containing lipids from substandard wakame and evaluation of its anticancer activities. In Annual Meeting of Society of Separation Process Engineers (Japan). Osaka.

  • Al-Rawi, M. A., Al-Jumaily, A., Lowe, A., & Lu, J. (2012). Stress phase angle for assesing atherosclerosis diseases located at the abdominal aorta. In Interprofessional Health Studies Poster Conference. Auckland.

  • Lu, J., Li, M., Pontre, B., Pickup, S., Phillips, A., & Cooper, G. (2012). SSAT inducer as a potential treatment for obesity-related heart failure. In 20th International Society for Magnetic Resonance in Medicine Vol. 20 (pp. 2635). Melbourne: ISMRM.

  • Al-Jumaily, A., White, D., Bartley, J., & Lu, J. (2011). Effects of augmented air pressure on the nasal erectile tissue and blood flow during breathing therapies. In Proceedings of the ASME 2011 International Mechanical Engineering Congress & Exposition, IMECE2011, Vol. track number IMECE2011-63132. Denver. Retrieved from http://www.asmeconferences.org/Congress2011/SearchPaperSchedule.cfm

  • Lu, J., Li, M., Tingle, M., Xu, H., & Cooper, G. (2011). Triethylenetetramine metabolism and its implication in cancer chemotherapy. In Proceedings of the 102nd Annual Meeting of the American Association for Cancer Research. Orlando, FL.. Retrieved from http://www.abstractsonline.com/

  • Lu, J., Pontre, B., Pickup, S., Choong, Y., Li, M., Phillips, A., . . . Young, A. A. (2010). Triethylenetetramine treatment in diabetic heart failure: An animal trial. In Proceedings of International Society for Magnetic Resonance in Medicine Vol. 18 (pp. 3640). Stockholm.

  • Lu, J., Li, M., Xu, H., Tingle, M., & Cooper, G. J. S. (2010). Spermidine/spermine acetyltransferase is responsible for the metabolism of triethylenetetramine and other polyamine analogs in humans. In 101st American Association for Cancer Research Annual Meeting Proceedings Supplement: Late-Breaking Section. Washington D.C.

  • Li, M., Pontre, B., Pickup, S., Xu, H., Phillips, A., Cooper, G. J. S., & Lu, J. (2010). Beneficial effects of diethylnorspermine in obesity and its cardiac complications. In Proceedings of International Society for Magnetic Resonance in Medicine Vol. 18 (pp. 2637). Stockholm.

Reports

  • Wang, A. J., White, L. N., Lu, J., Taylor, S., & White, W. L. (2014). Impact of processing and storage methods on the quantity and quality of fucoidan from NZ Undaria pinnatifida (14/02). Auckland University of Technology: Institute for Applied Ecology NZ.

  • White, L., Lu, Y., & White, W. L. (2014). Scoping assessment of the economic viability of harvesting Undaria pinnatifida from NZ mussel lines and potential uses of the collected material (14/01). Auckland, New Zealand: Institute for Applied Ecology.

Oral presentations

  • Lu, J. (2015). Biomedical use of New Zealand seaweed Undaria pinnatifida. 180 Gulf Harbour Drive, Whangaparaoa, Auckland.

  • Lu, J. (2010). Novel synthetic molecules for treatments of diabetic heart failure and cancer", public research seminar delivered on 11 May 2010 in the College of Chemistry and Chemical Engineering. Shenzhen University, Shenzhen, Guangdong Province, China.